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Erectile Dysfunction Treatment
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Tadalafil (Generic Cialis)10mg 4 Tablets Rear view of Tadalafil Tablets (2.5mg, 5mg, 10mg, 20mg)

Tadalafil Tablets (2.5mg, 5mg, 10mg, 20mg)

Tadalafil Tablets (2.5mg, 5mg, 10mg, 20mg) Product information

£8.95 (£2.24 per tablets)

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2.5mg 5mg 10mg 20mg
4 tablets - - £8.95 £9.49
8 tablets - - £14.97 £14.89
16 tablets - - £24.95 £24.95
28 tablets £24.99 £19.35 - -
32 tablets - - £43.59 £44.87
56 tablets £45.98 £36.89 - -
64 tablets - - £74.94 £74.94
84 tablets £62.95 £47.39 - -
168 tablets £124.99 £93.45 - -

What is Tadalafil?

Tadalafil film-coated tablets are part of a family of Erectile Dysfunction (ED) treatments, which can be taken as-needed or on a daily basis. They help to achieve and maintain an erection firm enough to enjoy fulfilling sexual intercourse.

Get to know more about Tadalafil and whether it’s the right solution for you.

The manufacturer of the product supplied may vary. Please read the patient information leaflet that is provided with the product. If you would like a specific brand, please do contact our customer services team.

Product Information for Tadalafil Tablets (2.5mg, 5mg, 10mg, 20mg)

About Tadalafil

The Tadalafil film-coated tablet is your flexible erection friend. It can be taken on-demand as needed or daily - you’re always prepared no matter the occasion. For daily use, we use 2.5mg or 5mg strengths and for as-needed use, we use 10mg or 20mg strengths.

Tadalafil key features

Often called the ‘weekend pill’, Tadalafil (when taken as needed) can last up to 36 hours – right through from Friday evening to Sunday morning. If you prefer to take the daily option instead, you’re always ready for action when the time comes.

Tadalafil is the generic version of the Cialis brand ED medication. This means they both contain the same active ingredient (Tadalafil).

As-needed option

Daily option

Oral tablet for ease

Oral tablet for ease

Works in as little as 30–60 minutes

Ready to go 24/7

Lasts up to 36 hours

Lasts until stopping daily use

 

Read more about taking Tadalafil in the Directions for Use section and remember to always fully read the Patient Information Leaflet that comes with the medication.

How does Tadalafil work for Erectile Dysfunction?

Tadalafil combats erectile dysfunction by targeting PDE5, an enzyme responsible for breaking down the natural chemical cGMP - which relaxes penile blood vessels.

The science simplified

During sexual arousal, the body releases nitric oxide into erectile tissues, which stimulates the production of cGMP. This chemical relaxes smooth muscle tissue and enhances blood flow into the penis.

Tadalafil works by stopping PDE5 breaking down cGMP, allowing this vessel-relaxing compound to build up and work longer. This prolonged action keeps blood vessels dilated, trapping adequate blood in the penis to maintain a firm erection.

Good to know

Tadalafil (when taken as needed) can begin to work within 30-60 minutes and can last for up to 36 hours. Other ED options may only last up to 4 hours, so Tadalafil can offer worry-free flexibility.

When taken daily, Tadalafil is always present in the body and allows for erections to be spontaneous in response to stimulation. You can relax in the moment knowing you have a helping hand.

With both options, Tadalafil will not give you an instant or uncontrollable erection, you still need to be sexually aroused.

Choosing the right Tadalafil dosage

Deciding to use either the daily or as-needed Tadalafil option depends on a combination of preference, lifestyle and sexual frequency.

Daily Tadalafil (2.5mg or 5mg)

This option provides continuous coverage without planning around sexual activity. It's ideal for those who have frequent sexual encounters (multiple times weekly) as it maintains a steady level in the bloodstream, allowing for spontaneity without waiting for medication to take effect. It can also have milder side effects since the dose is lower than as-needed versions. It's particularly suitable for couples in established relationships where intimacy occurs regularly but unpredictably. These daily tablets can take up to 2 weeks to be effective when you first start treatment.

As-needed Tadalafil (10mg or 20mg)

This option may appeal to those who have less frequent or more predictable sexual activity. It can be more cost-effective for occasional use - you're not taking medication on days without sexual activity. Some people may prefer not to take medication daily if it’s not needed. It offers a generous window of effectiveness (up to 36 hours), providing flexibility without daily commitment.

Am I eligible for Tadalafil tablets?

Tadalafil film-coated tablets are a prescription-only medication. The initial criteria below can help you work out if it’s the right treatment for you. A doctor will clinically review your completed online assessment before issuing a prescription.

  • Male (those assigned male at birth)

  • Aged 18 or over

Tadalafil might not be the right treatment for you if:  

  • You take nitrates for a heart condition. These are usually tablets or capsules called Isosorbide Mononitrate or Nicorandil (a medicine very similar to a nitrate) but can be called by other names

  • You use poppers

  • You have angina or have ever been given a spray that goes under your tongue to help chest pain

  • You have had a heart attack or stroke within the last three months

  • You have a condition called Peyronie’s or your penis has a bend when erect

  • You, or anyone in your family, has a history of eye disease, including retinitis pigmentosa or non-arteritic anterior ischaemic optic neuropathy (NAION)

  • You have liver or kidney problems

  • You have sickle-cell disease, multiple myeloma, or leukaemia

  • You have a stomach ulcer  

  • You have low blood pressure

  • You have uncontrolled high blood pressure

Get in touch with our team for a confidential and judgement-free chat about which Tadalafil option might be right for you. Call us on 01295 262925 or email help@oxfordop.co.uk

Tadalafil Tablets (2.5mg, 5mg, 10mg, 20mg) reviews

How to use Tadalafil Tablets (2.5mg, 5mg, 10mg, 20mg)

Tadalafil tablets should be swallowed whole with water and can be taken with or without food.

Because Tadalafil is available as both a daily treatment (2.5mg or 5mg) and an as-needed treatment (10mg or 20mg) for erectile dysfunction, instructions for when and how often you need to take it will depend on which one you’ve been prescribed.

Always read the Patient Information Leaflet included with your medication before starting treatment.

When should you take Tadalafil?

  • If you’ve been prescribed daily Tadalafil (2.5mg or 5mg), take ONE tablet once a day, ideally at the same time. You don’t need to plan when you take it around sex, as the medicine will build up to a steady level in your body.

  • If you’ve been prescribed Tadalafil to take when needed (10mg or 20mg), take ONE tablet at least 30 minutes before sex. Because Tadalafil lasts longer than some other erectile dysfunction treatments, there is usually less pressure to get the timing exactly right.

How often should you take Tadalafil?

How often you should take Tadalafil depends on which regimen you're on.

  • Daily Tadalafil: Take one tablet once a day only. It can take 1-2 weeks to reach full effect, so be patient and don’t take extra doses if it does not work straight away.

  • As-needed Tadalafil: Take when needed before sex, but never more than one dose in 24 hours. Since Tadalafil can work for up to 36 hours, you may not need another dose even if you have sex again the next day.

If you think your treatment is not working as expected, don’t adjust the dose yourself. Speak to one of our clinicians, who will check you’re taking it correctly and may suggest a higher-dose tablet or a different erectile dysfunction treatment.

How long does Tadalafil last?

If taken as needed, Tadalafil can remain effective for up to 36 hours, although this varies from person to person.

Daily Tadalafil works differently. Rather than giving a short-term effect, it provides continuous treatment and keeps a steady level of the medicine in your body, so you can be more spontaneous without needing to take a tablet before sex or plan around intimacy.

Important safety advice

If you miss a dose of daily Tadalafil, take it when you remember, unless it is nearly time for your next dose. Do not take two doses together.

If you have an erection lasting longer than 4 hours, seek urgent medical attention immediately.

Side effects of Tadalafil Tablets (2.5mg, 5mg, 10mg, 20mg)

These are some of the common side effects of Tadalafil tablets. This list isn’t exhaustive, and you should always read the Patient Information Leaflet that comes with your medication. A copy of this will also be in the medication packaging or box.

Common side effects (may affect up to 1 in 10 people)

  • Headaches

  • Flushing (hot, red skin usually on the upper body and face

  • Stuffy nose

  • Indigestion/heartburn

  • Muscle pain or back pain

The side effects listed below are more serious, and you should stop taking Tadalafil, and get medical help immediately.

  • An erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, seek medical help immediately. Priapism can permanently damage your penis.

  • Sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking Tadalafil and get medical help right away if you have sudden vision loss in one or both eyes.

  • Sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness. If you experience these symptoms, stop taking Tadalafil and contact a doctor right away.

If you would like to talk to our Healthcare Advisors about any concerns around side-effects please call us on 01295 262925 or email help@oxfordop.co.uk

Frequently Asked Questions
Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Tadalafil Tablets (2.5mg, 5mg, 10mg, 20mg) - Patient Information Leaflet

References
  1. Montorsi, F. et al. Long-term safety and tolerability of tadalafil in the treatment of erectile dysfunction. Eur. Urol. 45, 339–44; discussion 344–5 (2004).

Message From Our Pharmacist

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Authored on February 10, 2026

Reviewed on February 10, 2026

Kiran Jones

Kiran Jones - MPharm, MRPharmS

Pharmacist / Medical Content Writer

GPhC Number: 2071585